The Buffalo Bills front office is likely close to finalizing its Big Board for the 2025 NFL draft following the conclusion of the Scouting Combine. So, it’s time to take another crack at projecting all of the team’s selections with a seven-round mock draft.
This is our second attempt at this exercise since the offseason began. A glance at the first attempt will showcase some similarities, including the No. 30 overall pick, but also some differences. We’ll continue to operate under the belief Buffalo will upgrade its biggest need (edge rusher) via trade or free agency.
The 2025 NFL draft is scheduled to take place beginning April 24 at Lambeau Field, home of the Green Bay Packers.
Note: This mock draft is based on the Pro Football Network simulator, which attempts to project compensatory picks that haven’t been officially announced. The number of selections and their exact location will be finalized soon.
Buffalo Bills 7-Round 2025 Mock Draft (v2.0)
Round 1 (No. 30): Kenneth Grant (DT, Michigan)
Grant to Buffalo is one of the most logical fits in this year’s draft class. The Bills desperately need a monster defensive tackle to line up next to the smaller, more versatile Ed Oliver. Grant checks in at 6’4”, 331 pounds, and would bring some much-needed power to the middle of the defensive line. He met with the Bills during the combine.
Michigan DL Kenneth Grant confirms he has met with the #Bills at the combine. His impressions of that meeting: “Smooth.” #BillsMafia pic.twitter.com/15qk7Vr4s7
— alex brasky (@alexbrasky) February 26, 2025
Round 2 (No. 56): Isaiah Bond (WR, Texas)
Although Bond didn’t break Xavier Worthy’s combine record in the 40-yard dash, which is something he predicted, he still possesses game-breaking speed. That’s exactly what Buffalo needs. He’d be a perfect complement to fellow wide receivers Khalil Shakir and Keon Coleman. The Bills must win over the top more consistently.
Round 2 (No. 62): Andrew Mukuba (S, Texas)
A second straight member of the Longhorns for Buffalo. Mukuba showed impressive improvement in his play-reading ability during his senior season, which led to five interceptions. He’d immediately compete with Taylor Rapp and Cole Bishop for a starting role. He’s also capable of playing slot corner.
Round 4 (No. 108): Cobee Bryant (CB, Kansas)
The Bills will likely attempt to sign a veteran cornerback to a cheap one-year contract to fill the void left by free agent Rasul Douglas. They also need to start thinking about the future opposite Christian Benford, though. Bryant is a ball hawk (13 college INTs) who needs some work on technique to become a full-time NFL starter.
This is a Cobee Bryant rep if I’ve ever seen one:
Press alignment, early contact, little grab, punches the ball out at the catch point, stares down the receiver on the ground. The full experience pic.twitter.com/Yi38RY0aFp
— Trevor Sikkema (@TampaBayTre) January 26, 2025
Round 4 (No. 131): Antwaun Powell-Ryland (EDGE, Virginia Tech)
Powell-Ryland, who racked up 16 sacks for the Hokies in 2024, is one of the toughest projections in the class. His production and raw athleticism are impressive. Yet, he’s undersized and doesn’t possess elite small-area speed. He probably falls in the boom-or-bust category but is worth a mid-round flier for the Bills.
Round 5 (No. 171): Raheim Sanders (RB, South Carolina)
James Cook is making it no secret he’s seeking a lucrative contract extension. The Bills don’t have the financial flexibility to give him one this offseason unless it’s heavily back-loaded. Taking a versatile back like Sanders would provide clarity for the future as well as protection against a possible Cook holdout this year.
Round 5 (No. 175): Jack Kiser (LB, Notre Dame)
Kiser is reminiscent of a stay-at-home defenseman in hockey. While he doesn’t make a ton of flashy plays, he understands scheme well and is almost always in the right spot. The Bills have a terrific linebacker duo in Matt Milano and Terrel Bernard, but the defense has struggled when they are injured. Kiser could help bring stability.
#NotreDame LB Jack Kiser had a really clean positional workout last night. Thought this was one of his best reps. Could hear the other LBs buzzing louder and louder as it went on. pic.twitter.com/Ft0XpkXhuZ
— Fran Duffy (@FDuffyNFL) February 28, 2025
Round 6 (No. 179): Clay Webb (OG, Jacksonville State)
The Bills are set at offensive tackle with Dion Dawkins and Spencer Brown. The guard and center spots are less stabilized, though. Webb can play all three of the interior positions. He’s more of a developmental prospect but could still push David Edwards for playing time as a rookie.
Round 6 (No. 206): Que Robinson (EDGE, Alabama)
Robinson is a pedigree pick. He’s a former 4-star prospect who was on the fringe of the top 50 nationally coming out of high school. That never translated to big numbers with the Tide, though. He tallied just six sacks in 43 games amid limited playing time. He’d likely start his NFL career on special teams.
In a deep class of 3-4 OLBs, Que Robinson (6-5, 241) of #Alabama should be a mid-round target for pass rush needy teams. Has become a bit lost in the shuffle. Versatile, plays violent vs. the run, natural rusher and will be a core four special teams player right away. pic.twitter.com/iJO7Gr6isL
— Jordan Reid (@Jordan_Reid) February 17, 2025
Round 7 (No. 208): Alex Mastromanno (P, Florida State)
The Bills released Sam Martin, their punter for the last three years, ahead of free agency. They previously signed Jake Camarda to a reserve/future contract in January. Mastromanno would compete with Camarda in training camp after earning All-American honors in his final season at FSU.
Main Photo: Tim Heitman-Imagn Images
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